IKK beta Antibodies

Antibodies that detect IKK beta can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target IKK beta in Human, Mouse, Rat and Non-human primate samples. Our IKK beta polyclonal,... Antibodies that detect IKK beta can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target IKK beta in Human, Mouse, Rat and Non-human primate samples. Our IKK beta polyclonal, monoclonal and recombinant monoclonal... Antibodies that detect IKK beta can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target IKK beta in Human, Mouse, Rat and Non-human primate samples. Our IKK beta polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockdown to confirm specificity to IKK beta. Find the IKK beta antibody that fits your needs. Choose from 1 of 45 IKK beta antibodies, which have been validated in experiments with 90 publications and 108 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies... Antibodies that detect IKK beta can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target IKK beta in Human, Mouse, Rat and Non-human primate samples. Our IKK beta polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockdown to confirm specificity to IKK beta. Find the IKK beta antibody that fits your needs. Choose from 1 of 45 IKK beta antibodies, which have been validated in experiments with 90 publications and 108 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex. Inhibitor of nuclear factor kappa-B kinase subunit beta (IKK beta) is a serine kinase that plays an essential role in the NF-kaapa-B signaling pathway which is activated by mulitple stimuli such as inflammatory cytokines, bacterial, or viral products, DNA damages, or other cellular stresses. IKK beta acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. Mutations affecting the IKK beta gene can result in Immunodeficiency 15 (IMD15).

Synonyms

AI132552; AIM-1; FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; Ikbkb; IKK[b]; IKK2; IKK-2; IKKB; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta

Target Video

6320257098112

IKK beta antibodies from Thermo Fisher Scientific

https://cf-images.us-east-1.prod.boltdns.net/v1/static/3663210762001/0cda9f91-ce08-4195-b2b2-1a8dd1f6fe05/12d79228-8f7c-4422-8c3c-f986d91991c3/320x180/match/image.jpg

Learn more about IKK beta primary antibodies that can be used in Western Blot, Immunohistochemistry, Immunocytochemistry and ELISA in Human, Mouse, Rat and Non-human primate samples.

ikk beta

PT0M37S

2023-02-12T15:32:45.948Z

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IKK beta Antibodies

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